Description

tert-Butyl Rac-[(3S,5S)-5-Hydroxy-3-Piperidinyl]Carbamate is a chiral piperidine derivative carbamate, serving as a critical protected intermediate in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the synthesis of novel therapeutic agents and high-value specialty compounds.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a protected 5-hydroxy-3-piperidinyl moiety.
• Asymmetric Synthesis: Employed in stereoselective reactions to introduce chirality into target molecules for medicinal chemistry applications.
• Chemical Research: Serves as a versatile intermediate in academic and industrial research for developing new synthetic methodologies and exploring structure-activity relationships (SAR).
• Fine Chemical Production: Utilized in the manufacture of high-purity, specialty chemicals for advanced material science and agrochemical applications.
• Protecting Group Strategy: The tert-butyloxycarbonyl (Boc) group provides a stable, orthogonal protecting group for amines in complex multi-functional molecule synthesis.

Basic Information

Product Name	tert-Butyl Rac-[(3S,5S)-5-Hydroxy-3-Piperidinyl]Carbamate
CAS No.	1932116-79-4
Molecular Formula	C10H20N2O3
Molecular Weight	216.28 g/mol
Synonyms	rac-tert-Butyl (3S,5S)-5-hydroxy-3-piperidinecarboxylate; (±)-tert-Butyl (3S,5S)-5-hydroxypiperidine-3-carboxylate; tert-Butyl 5-hydroxy-3-piperidinecarboxylate (racemic mixture of (3S,5S) isomer); Boc-5-Hydroxy-3-piperidinecarboxylic acid tert-butyl ester (racemic); 1,1-Dimethylethyl rac-[(3S,5S)-5-hydroxy-3-piperidinyl]carbamate; 5-Hydroxy-3-piperidinecarboxylic acid tert-butyl ester; N-Boc-3S,5S-5-Hydroxypiperidine (racemic)
EINECS	Contact for details

Quality Control

Our tert-Butyl Rac-[(3S,5S)-5-Hydroxy-3-Piperidinyl]Carbamate is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Production adheres to current industry best practices, and each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support our clients' regulatory needs with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using a desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.