Description

tert-Butyl (2S,5R)-5-Ethyl-2-Methylpiperazine-1-Carboxylate is a high-purity, stereochemically defined piperazine derivative serving as a critical chiral building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs), particularly in the creation of complex molecules with specific stereochemical requirements. It is primarily utilized by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers focused on producing enantiomerically pure therapeutics.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of potential drug candidates, especially in central nervous system (CNS) and antiviral research.
• Asymmetric Catalyst Ligand Precursor: Used to develop novel chiral ligands for asymmetric catalysis, enhancing the enantioselectivity of chemical reactions.
• Peptidomimetic Chemistry: Incorporated into the backbone of peptidomimetics to improve metabolic stability and bioavailability of peptide-based drug leads.
• Agrochemical Research: Employed in the synthesis of chiral active ingredients for crop protection agents.
• Academic & Industrial R&D: Serves as a valuable reference standard and starting material for methodological development in synthetic organic chemistry.

Basic Information

Product Name	tert-Butyl (2S,5R)-5-Ethyl-2-Methylpiperazine-1-Carboxylate
CAS No.	1932079-78-1
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	1-Boc-(2S,5R)-5-ethyl-2-methylpiperazine; (2S,5R)-1-(tert-Butoxycarbonyl)-5-ethyl-2-methylpiperazine; tert-Butyl (2S,5R)-5-ethyl-2-methyl-1-piperazinecarboxylate; (2S,5R)-5-Ethyl-2-methylpiperazine-1-carboxylic acid tert-butyl ester; Boc-(2S,5R)-5-Et-2-Me-piperazine; (2S,5R)-N-Boc-5-ethyl-2-methylpiperazine; 1-N-Boc-(2S,5R)-5-ethyl-2-methylpiperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl (2S,5R)-5-Ethyl-2-Methylpiperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC to confirm stereochemical purity and identity. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles to ensure compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.