Description

2-Chloro-4-(4-Methylpiperazin-1-Yl)Benzoic Acid Hydrochloride is a high-purity, pharmaceutically relevant chemical intermediate, primarily valued for its role in the synthesis of complex active pharmaceutical ingredients (APIs). This compound is critical for research and development, offering a key building block for medicinal chemistry programs targeting a range of therapeutic areas. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and advanced chemical synthesis laboratories seeking reliable, high-quality intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic research.
• API Synthesis: Used in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs) requiring a substituted benzoic acid piperazine moiety.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Custom Synthesis: A starting material for the custom synthesis of more complex, proprietary molecules for client-specific R&D projects.

Basic Information

Product Name	2-Chloro-4-(4-Methylpiperazin-1-Yl)Benzoic Acid Hydrochloride
CAS No.	1910051-14-7
Molecular Formula	C13H18Cl2N2O2
Molecular Weight	305.20 g/mol
Synonyms	2-Chloro-4-(4-methyl-1-piperazinyl)benzoic acid hydrochloride; 4-(4-Methylpiperazin-1-yl)-2-chlorobenzoic acid hydrochloride; 2-Chloro-4-(4-methylpiperazin-1-yl)benzoic acid HCl; Benzoic acid, 2-chloro-4-(4-methyl-1-piperazinyl)-, hydrochloride (1:1); 1910051-14-7
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(4-Methylpiperazin-1-Yl)Benzoic Acid Hydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.