Description

3-Hydroxy-5-Methylpiperidine Hydrochloride is a high-purity, functionalized piperidine derivative, a key chiral building block in advanced organic synthesis. Its value lies in providing a versatile scaffold with both hydroxyl and amine functionalities, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of central nervous system (CNS) drugs, antiviral agents, and other therapeutic molecules.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its piperidine core for biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology & Proteomics: Employed as a building block for molecular probes and tool compounds to study biological systems.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring specific, high-value piperidine derivatives.
• Academic & R&D Laboratories: Used in medicinal chemistry programs for hit-to-lead optimization and structure-activity relationship (SAR) studies.

Basic Information

Product Name	3-Hydroxy-5-Methylpiperidine Hydrochloride
CAS No.	1909308-45-7
Molecular Formula	C6H14ClNO
Molecular Weight	151.63 g/mol
Synonyms	5-Methylpiperidin-3-ol hydrochloride; 3-Hydroxy-5-methylpiperidine HCl; 3-Hydroxy-5-methylpiperidine monohydrochloride; (3R,5S)-3-Hydroxy-5-methylpiperidine hydrochloride (if stereochemistry defined); (3S,5R)-3-Hydroxy-5-methylpiperidine hydrochloride; 5-Methyl-3-piperidinol hydrochloride; 3-Piperidinol, 5-methyl-, hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-5-Methylpiperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with key parameters including assay, chiral purity (if applicable), and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.