Description

Piperazine, 2-Methyl-1-(6-Nitro-3-Pyridinyl)-, (2S)- is a high-purity, chiral piperazine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical chiral building block or intermediate for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring stereochemical precision. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and process development of new drugs, agrochemicals, and other fine chemicals where its specific stereochemistry and functional groups are essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, especially for central nervous system (CNS) or anti-infective therapies.
• Agrochemical Synthesis: Used in the development of advanced pesticides or herbicides where the piperazine and nitropyridine motifs confer specific biological activity.
• Chemical Research: Serves as a valuable reference standard or starting material in academic and industrial laboratories for studying structure-activity relationships (SAR).
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex molecules in fine chemical manufacturing.
• Ligand & Catalyst Development: Potential precursor for creating novel chiral ligands or organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	Piperazine, 2-Methyl-1-(6-Nitro-3-Pyridinyl)-, (2S)-
CAS No.	1895867-66-9
Molecular Formula	C11H14N4O2
Molecular Weight	234.26 g/mol
Synonyms	(2S)-2-Methyl-1-(6-nitro-3-pyridinyl)piperazine; (S)-2-Methyl-1-(6-nitro-3-pyridinyl)piperazine; 1-(6-Nitro-3-pyridinyl)-2-methylpiperazine, (2S)-; 2-Methyl-1-(6-nitro-3-pyridinyl)piperazine, (S)-; (S)-1-(6-Nitro-3-pyridinyl)-2-methylpiperazine; 1895867-66-9; (2S)-1-(6-Nitropyridin-3-yl)-2-methylpiperazine
EINECS	Contact for details

Quality Control

Our Piperazine, 2-Methyl-1-(6-Nitro-3-Pyridinyl)-, (2S)- is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profiles is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.