Description

Butanedioic Acid, 2,3-Bis[(4-Methylbenzoyl)Oxy]-, (2R,3R)-, Compd. With Ethyl (2R,3S)-2-[4-(Cyclopentylamino)Phenyl]-3-Piperidinecarboxylate (2:1) is a high-purity, non-racemic salt complex designed for advanced pharmaceutical synthesis and research. This compound is critical for its role as a key chiral intermediate or building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily needed by R&D laboratories, process development chemists, and manufacturers in the pharmaceutical and fine chemical industries seeking reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of complex drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Process Chemistry & Scale-Up: Used in process research and development (PR&D) to optimize synthetic routes for new chemical entities (NCEs) before commercial manufacturing.
• Asymmetric Synthesis: Employed in reactions where the introduction of specific stereocenters is required, leveraging its defined (2R,3R) and (2R,3S) configurations.
• Reference Standard: Can be utilized as an analytical standard for method development and quality control in API manufacturing to ensure batch consistency and purity.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new biologically active molecules.
• Custom Synthesis: Acts as a starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Butanedioic Acid, 2,3-Bis[(4-Methylbenzoyl)Oxy]-, (2R,3R)-, Compd. With Ethyl (2R,3S)-2-[4-(Cyclopentylamino)Phenyl]-3-Piperidinecarboxylate (2:1)
CAS No.	1893415-79-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(2R,3R)-2,3-Bis(4-methylbenzoyloxy)succinic acid compound with ethyl (2R,3S)-2-[4-(cyclopentylamino)phenyl]-3-piperidinecarboxylate (2:1); Succinic acid, 2,3-bis[(4-methylbenzoyl)oxy]-, (2R,3R)-, compd. with ethyl (2R,3S)-2-[4-(cyclopentylamino)phenyl]-3-piperidinecarboxylate (2:1); Ethyl (2R,3S)-2-[4-(cyclopentylamino)phenyl]-3-piperidinecarboxylate (2:1) salt of (2R,3R)-2,3-di-p-toluoyloxy-succinic acid; CAS 1893415-79-6; Pharmaceutical intermediate 1893415-79-6.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques to confirm identity, purity, and chiral integrity. Certificates of Analysis (COA) detailing specific test results are available upon request. Our quality management system supports the stringent requirements of pharmaceutical development and manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.