Description

S-1,4-N,n-Boc-2-Methylpiperazine is a high-purity, protected piperazine derivative widely used as a key chiral building block in advanced organic synthesis. Its value lies in providing a stereochemically defined nitrogen-containing scaffold that is essential for constructing complex molecules with high enantiomeric purity. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs), novel drug candidates, and other fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the development of novel therapeutic agents, including kinase inhibitors, antiviral drugs, and central nervous system (CNS) active compounds.
• Asymmetric Synthesis: Serves as a versatile chiral auxiliary or ligand precursor in catalytic asymmetric reactions to introduce stereogenic centers.
• Peptidomimetics & PROTACs: Used in the construction of peptidomimetic structures and as a linker component in Proteolysis Targeting Chimeras (PROTACs) for targeted protein degradation.
• Agrochemical Research: Employed in the synthesis of chiral, biologically active molecules for crop protection and pesticide development.
• Chemical Biology Probes: Integral for creating tagged or modified chemical probes to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A requested building block for custom synthesis services catering to drug discovery and process chemistry needs.

Basic Information

Product Name	S-1,4-N,n-Boc-2-Methylpiperazine
CAS No.	1889308-20-6
Molecular Formula	C11H22N2O2
Molecular Weight	214.31 g/mol
Synonyms	(S)-1-Boc-2-Methylpiperazine; (S)-1-tert-Butoxycarbonyl-2-methylpiperazine; (S)-2-Methyl-1-(tert-butoxycarbonyl)piperazine; (S)-N-Boc-2-methylpiperazine; tert-Butyl (S)-2-methylpiperazine-1-carboxylate; (S)-1-N-Boc-2-methylpiperazine; (2S)-2-Methyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperazine; S-1,4-N-Boc-2-Methylpiperazine
EINECS	Contact for details

Quality Control

Our S-1,4-N,n-Boc-2-Methylpiperazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. Each lot undergoes comprehensive analytical testing, including chiral purity verification, to meet the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.