Description

I-Peg5-Oh CAS NO 1883516-31-1 is a high-purity, monodisperse polyethylene glycol (PEG) derivative featuring a terminal hydroxyl group, designed for precision conjugation and linker applications. This compound is critical for researchers and manufacturers requiring controlled hydrophilicity, solubility enhancement, and defined spacing in bioconjugation and pharmaceutical development. It serves as a fundamental building block for innovators in the pharmaceutical, biotechnology, and advanced materials sectors who need reliable, well-characterized PEG linkers.

Application

• Bioconjugation Linker: Used to conjugate drugs, proteins, or peptides to improve solubility, stability, and pharmacokinetic profiles.
• ADC (Antibody-Drug Conjugate) Development: Serves as a crucial spacer/component in the construction of next-generation ADCs, modulating the drug-antibody ratio and release kinetics.
• Polymer Chemistry: Acts as a monofunctional initiator or monomer for synthesizing well-defined block copolymers and functionalized materials.
• Surface Modification: Employed to PEGylate nanoparticles, quantum dots, and diagnostic agents to reduce immunogenicity and prolong circulation time.
• Cross-linking Agent: Utilized in hydrogel formation and biomaterial fabrication where a hydrophilic, biocompatible cross-linker is required.
• Solubility Enhancer: Incorporated into formulations to increase the aqueous solubility of poorly soluble active pharmaceutical ingredients (APIs).

Basic Information

Product Name	I-Peg5-Oh
CAS No.	1883516-31-1
Molecular Formula	C11H24O6
Molecular Weight	252.31 g/mol
Synonyms	2,5,8,11,14-Pentaoxaheptadecan-17-ol; 3,6,9,12,15-Pentaoxaheptadecan-1-ol; 17-Hydroxy-3,6,9,12,15-pentaoxaheptadecane; PEG5-OH; HO-PEG5-OH; 1-Hydroxy-3,6,9,12,15-pentaoxaheptadecane; Monohydroxy PEG5; Pentaglycol Monol
EINECS	Contact for details

Quality Control

Our I-Peg5-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and Karl Fischer titration for water content, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic nature. Allow the sealed container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Molecular Weight (NMR)	252.31 ± 2

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.