Description

2-Piperazinone, 4-(2-Pyrimidinyl)- is a heterocyclic organic compound featuring a piperazinone core fused with a pyrimidine moiety, serving as a sophisticated building block in advanced chemical synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries focused on creating new therapeutic agents and crop protection solutions.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Chemical Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic frameworks in medicinal and process chemistry.
• Academic & Institutional R&D: Employed in university and government laboratories for fundamental research in organic chemistry and pharmacology.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services for client projects.
• Material Science Exploration: Investigated as a potential monomer or additive for creating specialty polymers with unique properties.

Basic Information

Product Name	2-Piperazinone, 4-(2-Pyrimidinyl)-
CAS No.	1862847-95-7
Molecular Formula	C8H10N4O
Molecular Weight	178.19 g/mol
Synonyms	4-(Pyrimidin-2-yl)piperazin-2-one; 4-(2-Pyrimidinyl)-2-piperazinone; 2-Piperazinone, 4-(2-pyrimidinyl)-; 4-Pyrimidin-2-yl-piperazin-2-one; 1,4-Diazinan-2-one, 4-(2-pyrimidinyl)-; 4-(2-Pyrimidyl)piperazin-2-one; 4-(Pyrimidin-2-yl)-1,4-diazinan-2-one
EINECS	Contact for details

Quality Control

Our 2-Piperazinone, 4-(2-Pyrimidinyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. We support development and commercial projects requiring material that meets stringent internal specifications or compendial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.