Description

Methyl 2,5-Difluoro-4-Piperidin-1-Ylbenzoate is a high-purity, advanced pharmaceutical intermediate characterized by its distinct difluorinated benzoate ester structure. This compound is of significant commercial value for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring precise molecular modification. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and pesticides, leveraging the fluorine atoms for enhanced biological activity and stability.
• Chemical Synthesis: Used in organic synthesis for introducing the 2,5-difluoro-4-piperidin-1-ylbenzoate moiety into more complex molecular architectures.
• Material Science: Potential application in the development of specialty polymers and advanced materials where fluorinated aromatic compounds are required.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process development in academic and contract research organizations (CROs).

Basic Information

Product Name	Methyl 2,5-Difluoro-4-Piperidin-1-Ylbenzoate
CAS No.	1858241-61-8
Molecular Formula	C13H15F2NO2
Molecular Weight	255.26 g/mol
Synonyms	Methyl 2,5-difluoro-4-(piperidin-1-yl)benzoate; 2,5-Difluoro-4-(1-piperidinyl)benzoic Acid Methyl Ester; 4-Piperidin-1-yl-2,5-difluorobenzoic Acid Methyl Ester; Benzoic acid, 2,5-difluoro-4-(1-piperidinyl)-, methyl ester; Methyl 4-(piperidin-1-yl)-2,5-difluorobenzoate
EINECS	Contact for details

Quality Control

Our Methyl 2,5-Difluoro-4-Piperidin-1-Ylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.