Description

tert-Butyl 3-(2-Methoxy-2-oxoethyl)piperazine-1-carboxylate hydrochloride is a high-purity, protected piperazine derivative that serves as a critical building block in advanced organic synthesis. This compound is essential for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals, offering a versatile scaffold for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of complex molecules for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Peptidomimetic Synthesis: Employed in the construction of peptidomimetics and other biologically active compounds that incorporate modified piperazine structures.
• Custom Synthesis & Contract Manufacturing: Serves as a starting material or intermediate for custom synthesis services catering to the pharmaceutical and biotechnology industries.
• Chemical Library Development: Used in the generation of diverse chemical libraries for high-throughput screening (HTS) in early-stage drug discovery.

Basic Information

Product Name	tert-Butyl 3-(2-Methoxy-2-oxoethyl)piperazine-1-carboxylate hydrochloride
CAS No.	1858241-30-1
Molecular Formula	C12H23ClN2O4
Molecular Weight	294.78 g/mol
Synonyms	1-Boc-3-(2-methoxy-2-oxoethyl)piperazine hydrochloride; tert-Butyl 3-(carboxymethyl)piperazine-1-carboxylate hydrochloride methyl ester; 3-(2-Methoxy-2-oxoethyl)-1-(tert-butoxycarbonyl)piperazine hydrochloride; 1-(tert-Butoxycarbonyl)-3-(2-methoxy-2-oxoethyl)piperazine hydrochloride; Piperazine-1-carboxylic acid, 3-(2-methoxy-2-oxoethyl)-, 1,1-dimethylethyl ester, hydrochloride; Boc-3-(methoxycarbonylmethyl)piperazine HCl
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(2-Methoxy-2-oxoethyl)piperazine-1-carboxylate hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.