Description

2-Bromo-5-(2,2,2-trifluoroethoxy)pyrazine is a high-purity, advanced pharmaceutical intermediate characterized by its brominated pyrazine core and trifluoroethoxy side chain. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate halogenated heterocycles into their molecular designs.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides where the pyrazine moiety contributes to biological activity.
• Material Science Research: Serves as a precursor for the creation of specialty polymers and organic electronic materials.
• Chemical Biology Probes: Employed in the design of molecular probes and ligands for target identification and validation studies.
• Process Chemistry: Used in route scouting and optimization for the scalable production of complex molecules.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to R&D organizations.

Basic Information

Product Name	2-Bromo-5-(2,2,2-trifluoroethoxy)pyrazine
CAS No.	1857825-17-2
Molecular Formula	C6H4BrF3N2O
Molecular Weight	257.01 g/mol
Synonyms	2-Bromo-5-(2,2,2-trifluoroethoxy)pyrazine; 5-Bromo-2-(2,2,2-trifluoroethoxy)pyrazine; Pyrazine, 2-bromo-5-(2,2,2-trifluoroethoxy)-; 1857825-17-2; 2-(2,2,2-Trifluoroethoxy)-5-bromopyrazine; 5-Bromo-2-(trifluoroethoxy)pyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(2,2,2-trifluoroethoxy)pyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.