Description

tert-Butyl3-Bromo-2-(4-Fluorophenyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate (Wx155050) is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure with bromo and fluoro substituents. This compound is a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery programs.
• Kinase Inhibitor Synthesis: A valuable scaffold for constructing potential kinase inhibitors, a major class of targeted cancer therapies.
• CNS Drug Development: Employed in the synthesis of compounds targeting neurological disorders due to its specific heterocyclic core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Used in university and institutional labs for exploratory organic synthesis and methodological studies.

Basic Information

Product Name	tert-Butyl3-Bromo-2-(4-Fluorophenyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate (Wx155050)
CAS No.	1847458-10-9
Molecular Formula	C20H21BrFN3O2
Molecular Weight	434.31 g/mol
Synonyms	tert-Butyl 3-bromo-2-(4-fluorophenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-5-carboxylate; WX-155050; 5H-6,7-Dihydropyrazolo[1,5-a]pyrazine-5-carboxylic acid, 3-bromo-2-(4-fluorophenyl)-, 1,1-dimethylethyl ester; 3-Bromo-2-(4-fluorophenyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carboxylic acid tert-butyl ester; BOC-protected bromo-fluorophenyl dihydropyrazolopyrazine; tert-Butyl 3-bromo-2-(p-fluorophenyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl3-Bromo-2-(4-Fluorophenyl)-6,7-Dihydropyrazolo[1,5-A]Pyrazine-5(4H)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.