Description

5-Bromo-3-Cyclopropylpyrazin-2-Amine is a high-purity, functionalized pyrazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of bromine and amine functional groups on the pyrazine core, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialty polymers and organic electronic materials.
• Chemical Synthesis: Acts as a versatile building block for further functionalization via cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) due to the reactive bromine substituent.
• Academic & Contract Research: Employed in medicinal chemistry programs and discovery research for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Bromo-3-Cyclopropylpyrazin-2-Amine
CAS No.	1845754-43-9
Molecular Formula	C7H8BrN3
Molecular Weight	214.06 g/mol
Synonyms	5-Bromo-3-cyclopropyl-2-pyrazinamine; 3-Cyclopropyl-5-bromopyrazin-2-amine; 2-Amino-5-bromo-3-cyclopropylpyrazine; 5-Bromo-3-cyclopropylpyrazin-2-ylamine; 1845754-43-9; 5-Bromo-3-cyclopropyl-2-aminopyrazine
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-Cyclopropylpyrazin-2-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.