Description

Urea, n-[(3S,4R)-4-(3-Fluorophenyl)-1-(2-Methoxyethyl)-3-Pyrrolidinyl]-N'-[4-Methyl-3-(2-Methyl-5-Pyrimidinyl)-1-Phenyl-1H-Pyrazol-5-Yl]- is a high-purity, non-natural urea derivative featuring a complex, multi-ring heterocyclic structure. This compound is of significant interest as a key pharmaceutical intermediate or active pharmaceutical ingredient (API) building block in modern drug discovery and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly within oncology and targeted therapy research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new chemical entities.
• Biochemical Research: Acts as a specialized tool compound for probing biological pathways and enzyme functions in vitro.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Reference Standard: Can be used as an analytical standard for method development and quality control in API manufacturing.

Basic Information

Item	Details
Product Name	Urea, n-[(3S,4R)-4-(3-Fluorophenyl)-1-(2-Methoxyethyl)-3-Pyrrolidinyl]-N'-[4-Methyl-3-(2-Methyl-5-Pyrimidinyl)-1-Phenyl-1H-Pyrazol-5-Yl]-
CAS No.	1824664-89-2
Molecular Formula	C29H32FN7O2
Molecular Weight	529.61 g/mol
Synonyms	1-(2-Methoxyethyl)-4-(3-fluorophenyl)-3-({[4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1H-pyrazol-5-yl]carbamoyl}amino)pyrrolidine; (3S,4R)-1-(2-Methoxyethyl)-4-(3-fluorophenyl)-N-{[4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1H-pyrazol-5-yl]carbamoyl}pyrrolidin-3-amine; UNII-7K4K6F4K6I (proposed); Urea derivative of substituted pyrrolidine and pyrazole; Complex heterocyclic urea.
EINECS	Contact for details

Quality Control

Our Urea, n-[(3S,4R)-4-(3-Fluorophenyl)-1-(2-Methoxyethyl)-3-Pyrrolidinyl]-N'-[4-Methyl-3-(2-Methyl-5-Pyrimidinyl)-1-Phenyl-1H-Pyrazol-5-Yl]- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from HPLC, NMR, and MS are provided, confirming compliance with client specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.