Description

6-Bromo-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine is a high-value, multi-functional heterocyclic building block designed for advanced synthetic chemistry. This compound is engineered to provide a trifluoromethylated and halogenated core, offering unique reactivity and physicochemical properties for creating novel molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and insecticides, leveraging the stability and lipophilicity imparted by the trifluoromethyl group.
• Material Science Research: Serves as a precursor for the development of advanced organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Employed in the creation of tagged molecules and probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromine atom provides an excellent handle for versatile palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Fluorine Chemistry Building Block: The trifluoromethyl group makes it a valuable scaffold for introducing fluorine atoms to modulate bioavailability, metabolic stability, and binding affinity.

Basic Information

Product Name	6-Bromo-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine
CAS No.	1824284-78-7
Molecular Formula	C6H2BrF3N4
Molecular Weight	266.01 g/mol
Synonyms	6-Bromo-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine; 2-(Trifluoromethyl)-6-bromo-[1,2,4]triazolo[1,5-a]pyrazine; [1,2,4]Triazolo[1,5-a]pyrazine, 6-bromo-2-(trifluoromethyl)-; 6-Bromo-2-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyrazine; 1824284-78-7; 6-Bromo-2-(trifluoromethyl)-1,2,4-triazolo[1,5-a]pyrazine
EINECS	Contact for details

Quality Control

Our 6-Bromo-2-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.