Description

(5,5-Difluoropiperidin-2-Yl)Methanol Hydrochloride is a high-purity, fluorinated piperidine derivative supplied as a hydrochloride salt. This compound serves as a critical advanced pharmaceutical intermediate (API intermediate) for the synthesis of novel bioactive molecules. It is primarily utilized by research organizations and pharmaceutical companies engaged in drug discovery and development, particularly for candidates targeting neurological disorders and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those requiring a fluorinated piperidine scaffold.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Protease Inhibitor Development: Serves as a precursor for inhibitors targeting specific enzymes.
• Ligand Synthesis for Receptor Studies: Employed in creating novel ligands for pharmacological profiling and target validation.
• Chemical Biology Probes: Utilized in the development of tool compounds for investigating biological pathways.
• Agrochemical Research: Potential intermediate for developing new active ingredients with enhanced properties.

Basic Information

Product Name	(5,5-Difluoropiperidin-2-Yl)Methanol Hydrochloride
CAS No.	1823930-16-0
Molecular Formula	C7H12ClF2NO
Molecular Weight	199.63 g/mol
Synonyms	2-(Hydroxymethyl)-5,5-difluoropiperidine hydrochloride; 5,5-Difluoro-2-piperidinemethanol hydrochloride; (5,5-Difluoropiperidin-2-yl)methanol HCl; 5,5-Difluoropiperidine-2-methanol hydrochloride; 2-(Hydroxymethyl)-5,5-difluoropiperidine HCl; 5,5-Difluoro-2-(hydroxymethyl)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our (5,5-Difluoropiperidin-2-Yl)Methanol Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.