Description

5-tert-Butyl 7-Ethyl 6,7-Dihydropyrazolo[1,5-A]Pyrazine-5,7(4H)-Dicarboxylate (Wx141845) is a high-purity, advanced pharmaceutical intermediate belonging to the dihydropyrazolopyrazine class of heterocyclic compounds. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting complex diseases. Research and development teams in the pharmaceutical and biotechnology sectors require this precise chemical scaffold to develop new therapeutic agents with potential applications in oncology and central nervous system disorders.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the research and development of new drug candidates, especially for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery pipelines.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex nitrogen-containing heterocycles due to its reactive ester groups and fused ring system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities for clinical trials.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces in organic and medicinal chemistry.

Basic Information

Product Name	5-tert-Butyl 7-Ethyl 6,7-Dihydropyrazolo[1,5-A]Pyrazine-5,7(4H)-Dicarboxylate (Wx141845)
CAS No.	1823856-54-7
Molecular Formula	C16H23N3O4
Molecular Weight	321.37 g/mol
Synonyms	WX-141845; Wx141845; 5-(tert-Butyl) 7-ethyl 6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5,7-dicarboxylate; 5-tert-Butoxycarbonyl-7-ethoxycarbonyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine; Ethyl 5-(tert-butoxycarbonyl)-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-7-carboxylate; tert-Butyl 7-ethoxycarbonyl-6,7-dihydro-4H-pyrazolo[1,5-a]pyrazine-5-carboxylate; 6,7-Dihydro-4H-pyrazolo[1,5-a]pyrazine-5,7-dicarboxylic acid, 5-(1,1-dimethylethyl) 7-ethyl ester
EINECS	Contact for details

Quality Control

Our 5-tert-Butyl 7-Ethyl 6,7-Dihydropyrazolo[1,5-A]Pyrazine-5,7(4H)-Dicarboxylate (Wx141845) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.