Description

2-Bromo-7-(tert-Butoxycarbonyl)-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-3-Carboxylic Acid is a sophisticated heterocyclic building block of significant interest in modern pharmaceutical research and development. This compound is valued for its role as a key synthetic intermediate in the construction of complex molecules, particularly those targeting central nervous system and metabolic disorders. It is primarily utilized by medicinal chemists and process development scientists in pharmaceutical, biotechnology, and advanced fine chemical synthesis sectors.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric drug candidates.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for potential drug substances under Good Manufacturing Practice (GMP) guidelines.
• Bioconjugation & Probe Development: The carboxylic acid and bromo functional groups allow for further derivatization, making it suitable for creating chemical probes or bioconjugates for biological testing.
• Academic & Contract Research: Employed in academic laboratories and by contract research organizations (CROs) for exploratory synthetic projects and methodological studies.

Basic Information

Item	Details
Product Name	2-Bromo-7-(tert-Butoxycarbonyl)-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-3-Carboxylic Acid
CAS No.	1823840-73-8
Molecular Formula	C₁₂H₁₆BrN₃O₄
Molecular Weight	346.18 g/mol
Synonyms	2-Bromo-7-Boc-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-3-carboxylic acid; 7-(tert-Butoxycarbonyl)-2-bromo-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-3-carboxylic acid; 2-Bromo-7-[(2-methylpropan-2-yl)oxycarbonyl]-5,6,7,8-tetrahydroimidazo[1,2-a]pyrazine-3-carboxylic acid; Boc-protected 2-bromo-tetrahydroimidazopyrazine carboxylic acid; Imidazo[1,2-a]pyrazine-3-carboxylic acid, 2-bromo-5,6,7,8-tetrahydro-7-[(1,1-dimethylethoxy)carbonyl]-
EINECS	Contact for details

Quality Control

Our production of 2-Bromo-7-(tert-Butoxycarbonyl)-5,6,7,8-Tetrahydroimidazo[1,2-A]Pyrazine-3-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, essential for research and development applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.