Description

5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-7-carboxylic acid is a high-purity, advanced pharmaceutical intermediate featuring a complex bicyclic heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process chemistry for oncology and inflammatory diseases.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up API synthesis under GMP conditions.
• Bioconjugation & Probe Synthesis: The carboxylic acid functional group allows for conjugation to other molecules, useful in creating chemical probes for biological assays.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-7-carboxylic Acid
CAS No.	1823815-24-2
Molecular Formula	C₁₃H₁₉N₃O₄
Molecular Weight	281.31 g/mol
Synonyms	Boc-Pyrazolo-Pyrazine-7-Carboxylic Acid; 7-Carboxy-5-[(2-methylpropan-2-yl)oxycarbonyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine; 5-Boc-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-7-carboxylic acid; tert-Butyl 7-carboxy-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-5-carboxylate; Pyrazolo[1,5-a]pyrazine-7-carboxylic acid, 4,5,6,7-tetrahydro-5-[(1,1-dimethylethoxy)carbonyl]-; 1823815-24-2
EINECS	Contact for details

Quality Control

Our production of 5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-7-carboxylic acid adheres to stringent quality protocols suitable for pharmaceutical R&D and development. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under a dry atmosphere to prevent degradation. For long-term storage, consider storing under an inert gas such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.