Description

tert-Butyl (S)-3-((Methylamino)Methyl)Piperidine-1-Carboxylate is a high-purity, chiral piperidine derivative protected with a Boc (tert-butoxycarbonyl) group. This compound is a critical pharmaceutical intermediate and building block for medicinal chemistry research, enabling the synthesis of complex molecules with defined stereochemistry. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and lead optimization due to its functionalized piperidine scaffold and protected amine.
• Process Chemistry: Serves as a starting material or advanced intermediate in the scale-up and commercial manufacturing of active pharmaceutical ingredients (APIs).
• Agrochemical Research: Employed in the development of new pesticides and herbicides where specific stereochemistry is required for biological activity.
• Chemical Biology Probes: Useful for creating labeled compounds or probes to study biological pathways and enzyme interactions.
• Custom Synthesis: A versatile substrate for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Product Name	tert-Butyl (S)-3-((Methylamino)Methyl)Piperidine-1-Carboxylate
CAS No.	1821837-42-6
Molecular Formula	C13H26N2O2
Molecular Weight	242.36 g/mol
Synonyms	1-Boc-3-((Methylamino)Methyl)-(S)-Piperidine; (S)-1-(tert-Butoxycarbonyl)-3-((methylamino)methyl)piperidine; (S)-tert-Butyl 3-((methylamino)methyl)piperidine-1-carboxylate; (S)-3-((Methylamino)Methyl)Piperidine-1-Carboxylic Acid tert-Butyl Ester; (S)-N-Boc-3-(Aminomethyl)-N-Methylpiperidine; (S)-N-Boc-3-((Methylamino)Methyl)Piperidine; 1821837-42-6; (S)-1-N-Boc-3-(N-Methylaminomethyl)piperidine
EINECS	Contact for details

Quality Control

Our tert-Butyl (S)-3-((Methylamino)Methyl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and spectroscopic identification (NMR, IR) are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.