Description

(2S,5R)-5-Ethyl-1,2-Dimethylpiperazine is a high-purity, stereochemically defined chiral piperazine derivative. This compound is a critical building block in the synthesis of advanced pharmaceutical intermediates and fine chemicals, where its specific stereochemistry is essential for biological activity and process control. It is primarily required by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand: Used as a precursor or framework for synthesizing chiral ligands in asymmetric catalysis for enantioselective synthesis.
• Agrochemical Research: Serves as a building block for novel chiral pesticides and herbicides, where stereochemistry impacts efficacy and environmental profile.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals requiring specific piperazine motifs.
• Academic & R&D: Utilized in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction pathways.

Basic Information

Product Name	(2S,5R)-5-Ethyl-1,2-Dimethylpiperazine
CAS No.	1821806-85-2
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	(2S,5R)-5-Ethyl-1,2-dimethylpiperazine; (2S,5R)-5-Ethyl-1,2-dimethyl-piperazine; 5-Ethyl-1,2-dimethylpiperazine, (2S,5R)-; (2S,5R)-1,2-Dimethyl-5-ethylpiperazine; 1,2-Dimethyl-5-ethylpiperazine, (2S,5R)-; (2S,5R)-5-Ethyl-1,2-dimethylhexahydropyrazine; UNII-9J3F6S90L2 (FDA UNII Code)
EINECS	Contact for details

Quality Control

Our (2S,5R)-5-Ethyl-1,2-Dimethylpiperazine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.