Description

tert-Butyl (R)-(2-(Piperidin-2-Yl)Ethyl)Carbamate is a high-purity, chiral building block and Boc-protected intermediate of significant value in advanced organic synthesis. Its primary importance lies in its role as a key precursor for the development of novel pharmaceutical compounds, particularly those targeting neurological and receptor-based therapies. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) drug discovery.
• Peptidomimetic Research: Used in the design and construction of peptidomimetics and constrained peptide analogs due to its piperidine-ethyl backbone.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Agrochemical Synthesis: Employed in the research phase for creating novel, enantiomerically pure agrochemicals with specific biological activity.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules in chemical biology studies to investigate protein function.

Basic Information

Item	Detail
Product Name	tert-Butyl (R)-(2-(Piperidin-2-Yl)Ethyl)Carbamate
CAS No.	1821791-75-6
Molecular Formula	C12H24N2O2
Molecular Weight	228.33 g/mol
Synonyms	(R)-2-(2-((tert-Butoxycarbonyl)amino)ethyl)piperidine; (R)-N-Boc-2-(2-aminoethyl)piperidine; (R)-1-Boc-2-(2-aminoethyl)piperidine; (R)-tert-Butyl 2-(2-piperidin-2-ylethyl)carbamate; (R)-N-(tert-Butoxycarbonyl)-2-(2-piperidin-2-ylethyl)amine; Boc-(R)-2-(2-Aminoethyl)piperidine; (R)-Boc-AEP
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl (R)-(2-(Piperidin-2-Yl)Ethyl)Carbamate is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the product meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity (typically ≥97% by HPLC), enantiomeric excess, and impurity profiles. Our quality protocols are designed to support cGMP and ISO compliant applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.