Description

tert-Butyl ((3As,4S,6Ar)-Octahydrocyclopenta[C]Pyrrol-4-Yl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a complex, stereochemically defined cyclopenta[C]pyrrolidine scaffold. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within central nervous system (CNS) and antiviral research pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of complex drug molecules.
• Protease Inhibitor Research: Used in the development of novel inhibitors targeting specific viral or human proteases.
• Neurological Drug Discovery: Employed as a precursor in the synthesis of potential therapeutics for CNS disorders.
• Asymmetric Synthesis: Utilized in chiral pool synthesis due to its defined stereocenters, enabling the construction of enantiomerically pure compounds.
• Medicinal Chemistry Research: Provides a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	tert-Butyl ((3As,4S,6Ar)-Octahydrocyclopenta[C]Pyrrol-4-Yl)Carbamate
CAS No.	1821743-21-8
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	Boc-(3aS,4S,6aR)-Octahydrocyclopenta[c]pyrrol-4-amine; (3aS,4S,6aR)-4-[(tert-Butoxycarbonyl)amino]octahydrocyclopenta[c]pyrrole; tert-Butyl N-[(3aS,4S,6aR)-octahydrocyclopenta[c]pyrrol-4-yl]carbamate; (3aS,4S,6aR)-4-(Boc-amino)hexahydro-1H-cyclopenta[c]pyrrole; BOC-Protected Cyclopentapyrrolidine Amine; (3aS,4S,6aR)-Octahydrocyclopenta[c]pyrrol-4-yl-carbamic Acid tert-Butyl Ester
EINECS	Contact for details

Quality Control

Our tert-Butyl ((3As,4S,6Ar)-Octahydrocyclopenta[C]Pyrrol-4-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for advanced pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.