Description

Incb057643 CAS NO 1820889-23-3 is a high-purity, small molecule compound of significant interest in advanced pharmaceutical research and development. Its primary value lies in its role as a potent and selective inhibitor for targeted therapeutic applications, offering researchers a critical tool for probing disease mechanisms. This product is essential for biotechnology firms, pharmaceutical companies, and academic research institutions engaged in oncology, immunology, and metabolic disorder studies.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and preclinical development of novel therapeutics.
• Oncology Research: Used in biochemical and cellular assays to study specific kinase pathways involved in cancer cell proliferation and survival.
• Biochemical Tool Compound: Employed as a selective inhibitor to validate drug targets and understand signal transduction pathways in various disease models.
• Preclinical Studies: Utilized in in vitro and in vivo studies to establish proof-of-concept, pharmacokinetics, and pharmacodynamics for new drug candidates.
• High-Throughput Screening (HTS): Acts as a control or benchmark compound in screening campaigns to identify new lead molecules with similar mechanisms of action.

Basic Information

Product Name	Incb057643
CAS No.	1820889-23-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	INCB-057643; INCB057643; INCB 057643; (S)-N-(5-(3-(3,4-Dihydroisoquinolin-2(1H)-yl)-2-hydroxypropoxy)-1H-indazol-6-yl)-3,4-difluorobenzamide; 3,4-Difluoro-N-[6-[[(2S)-3-(3,4-dihydro-1H-isoquinolin-2-yl)-2-hydroxy-propoxy]-1H-indazol-5-yl]benzamide
EINECS	Contact for details

Quality Control

Every batch of Incb057643 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are suitable for research use and are supported by a detailed Certificate of Analysis (COA) that includes data from advanced techniques such as HPLC, NMR, and mass spectrometry. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term storage (up to 4 weeks), the product may be kept at 2-8°C. The material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled, dry environment to maintain purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.