Description

3-(3-Amino-5-Chloro-2-Oxo-2H-Pyrazin-1-Yl)-Benzoic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a defined heterocyclic structure. This compound matters for its critical role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. Pharmaceutical R&D and fine chemical manufacturers need this ester for developing next-generation drug candidates, leveraging its reactive sites for further functionalization.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug molecules, especially in oncology and antiviral research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core scaffold for constructing novel APIs targeting specific biological pathways.
• Chemical Research & Development: Used in academic and industrial labs for exploring new chemical entities and reaction methodologies involving pyrazinone and benzoate systems.
• Agrochemical Synthesis: Potential intermediate for developing advanced crop protection agents with specific modes of action.
• Material Science Precursor: Can be utilized in the synthesis of specialty polymers or organic electronic materials requiring functionalized heterocyclic components.

Basic Information

Product Name	3-(3-Amino-5-Chloro-2-Oxo-2H-Pyrazin-1-Yl)-Benzoic Acid Methyl Ester
CAS No.	1820712-46-6
Molecular Formula	C12H10ClN3O3
Molecular Weight	279.68 g/mol
Synonyms	Methyl 3-(3-amino-5-chloro-2-oxo-2H-pyrazin-1-yl)benzoate; 1H-Pyrazin-2-one, 3-amino-5-chloro-1-[3-(methoxycarbonyl)phenyl]-; 3-Amino-5-chloro-1-[3-(methoxycarbonyl)phenyl]-1H-pyrazin-2-one; Benzoic acid, 3-(3-amino-5-chloro-2-oxo-2H-pyrazin-1-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our 3-(3-Amino-5-Chloro-2-Oxo-2H-Pyrazin-1-Yl)-Benzoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.