Description

tert-Butyl 4-(4-Bromo-3-Chlorophenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with halogenated aromatic substituents. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with targeted biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization due to its modifiable piperazine and halogenated phenyl groups.
• Process Chemistry Development: Serves as a critical intermediate in scaling up synthetic routes for Active Pharmaceutical Ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.
• Agrochemical Synthesis: Employed in the research and development of novel herbicides, fungicides, and insecticides.
• Chemical Biology Probes: Useful for creating labeled compounds or probes to study biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis services catering to specific client requirements in fine chemical production.

Basic Information

Item	Details
Product Name	tert-Butyl 4-(4-Bromo-3-Chlorophenyl)Piperazine-1-Carboxylate
CAS No.	1820703-82-9
Molecular Formula	C15H20BrClN2O2
Molecular Weight	375.69 g/mol
Synonyms	1-Boc-4-(4-Bromo-3-chlorophenyl)piperazine; tert-Butyl 4-(4-bromo-3-chlorophenyl)piperazine-1-carboxylate; 4-(4-Bromo-3-chlorophenyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(4-bromo-3-chlorophenyl)piperazine; Boc-4-(4-Bromo-3-chlorophenyl)piperazine; N-Boc-4-(4-Bromo-3-chlorophenyl)piperazine; 1820703-82-9
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 4-(4-Bromo-3-Chlorophenyl)Piperazine-1-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are characterized using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC / MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.