Description

(R)-Ethyl Morpholine-2-Carboxylate Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant commercial importance. Its defined stereochemistry makes it a critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and other fine chemicals requiring precise molecular architecture. This compound is essential for research and development laboratories, process chemists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of novel therapeutic agents, particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis: Used as a starting material or catalyst ligand in stereoselective chemical reactions to create enantiomerically pure compounds.
• API Development: Serves as a crucial building block in the synthetic pathways of complex drug molecules during preclinical and process development stages.
• Agrochemical Research: Employed in the synthesis of chiral pesticides and herbicides where specific stereochemistry impacts biological activity.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry programs.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances that require high-purity chiral components.

Basic Information

Product Name	(R)-Ethyl Morpholine-2-Carboxylate Hydrochloride
CAS No.	1820569-61-6
Molecular Formula	C7H14ClNO3
Molecular Weight	195.65 g/mol
Synonyms	(R)-Ethyl 2-Morpholinecarboxylate Hydrochloride; (R)-Morpholine-2-carboxylic Acid Ethyl Ester Hydrochloride; Ethyl (R)-Morpholine-2-carboxylate Hydrochloride; (2R)-Morpholine-2-carboxylic Acid Ethyl Ester Hydrochloride; (R)-2-Morpholinecarboxylic Acid Ethyl Ester Hydrochloride; (R)-2-(Ethoxycarbonyl)morpholine Hydrochloride; UNII-Contact for details; (R)-EMC HCl
EINECS	Contact for details

Quality Control

Our (R)-Ethyl Morpholine-2-Carboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support compliance with ICH Q7 guidelines and can tailor specifications to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.