Description

7-Bromo-5-(4-Methylbenzenesulfonyl)-5H-Pyrrolo[2,3-B]Pyrazine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. This compound is critical for research and development in the pharmaceutical and agrochemical sectors, where it serves as a key intermediate for creating novel active ingredients. Its unique pyrrolopyrazine core, functionalized with bromo and tosyl groups, offers versatile reactivity for cross-coupling and further derivatization, enabling the construction of complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Employed as a molecular probe or a tag in proteomics and bio-conjugation studies due to its reactive bromine handle.
• Academic & Contract Research: Essential for medicinal chemistry programs and discovery research in academic institutions and CROs (Contract Research Organizations).
• Custom Synthesis: A starting material for the custom manufacturing of complex, proprietary compounds for client-specific projects.

Basic Information

Product Name	7-Bromo-5-(4-Methylbenzenesulfonyl)-5H-Pyrrolo[2,3-B]Pyrazine
CAS No.	1818847-41-4
Molecular Formula	C₁₃H₁₀BrN₃O₂S
Molecular Weight	352.21 g/mol
Synonyms	7-Bromo-5-tosyl-5H-pyrrolo[2,3-b]pyrazine; 5H-Pyrrolo[2,3-b]pyrazine, 7-bromo-5-[(4-methylphenyl)sulfonyl]-; 7-Bromo-5-(p-toluenesulfonyl)-5H-pyrrolo[2,3-b]pyrazine; 7-Bromo-5-(toluene-4-sulfonyl)-5H-pyrrolo[2,3-b]pyrazine; Tosyl-protected 7-bromopyrrolopyrazine; 7-Br-5-Ts-Pyrrolo[2,3-b]pyrazine; Pyrrolo[2,3-b]pyrazine, 7-bromo-5-(4-methylbenzenesulfonyl)-5H-
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-(4-Methylbenzenesulfonyl)-5H-Pyrrolo[2,3-B]Pyrazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports applications requiring high-purity intermediates for GMP (Good Manufacturing Practice) and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.