Description

Amino-Peg10-Acid CAS NO 1818294-41-5 is a heterobifunctional polyethylene glycol (PEG) derivative featuring a primary amine group and a terminal carboxylic acid, connected by a ten-unit PEG spacer. This bifunctionality is critical for creating stable, hydrophilic, and biocompatible crosslinks in advanced bioconjugation and materials science applications. It is an essential building block for researchers and manufacturers in the pharmaceutical, diagnostics, and biomaterials sectors who require precise, water-soluble linkers for modifying peptides, proteins, and surfaces.

Application

• Conjugation reagent for attaching amine-containing molecules (e.g., peptides, proteins, antibodies) to carboxylated surfaces or other molecules.
• Key intermediate in the synthesis of antibody-drug conjugates (ADCs) and other targeted therapeutic bioconjugates.
• Functionalization agent for nanoparticles and liposomes to improve solubility, stability, and targeting capabilities.
• Building block for creating hydrogels and smart biomaterials with controlled degradation and release profiles.
• Surface modification of biosensors and diagnostic assay platforms to enhance biocompatibility and reduce non-specific binding.
• Intermediate in the production of specialized PEGylated reagents and crosslinkers for life science research.

Basic Information

Product Name	Amino-Peg10-Acid
CAS No.	1818294-41-5
Molecular Formula	C24H49NO13
Molecular Weight	583.65 g/mol
Synonyms	15-Amino-4,7,10,13-tetraoxapentadecanoic Acid; α-Amino-ω-carboxy-tetraethylene glycol; H2N-PEG10-COOH; Amine-PEG10-Acid; Amino-PEG10-carboxylic acid; 2,5,8,11,14,17,20,23,26,29-Decaoxa-32-azatetratriacontan-34-oic acid; NH2-PEG10-COOH; 15-Amino-4,7,10,13-tetraoxapentadecanoic acid
EINECS	Contact for details

Quality Control

Our Amino-Peg10-Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for research and bioconjugation applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 90% (by titration)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.