Description

2,3-Dichloro-5-Iodopyrazine is a high-value halogenated heterocyclic building block essential for advanced organic synthesis. This compound is particularly significant for its role as a versatile intermediate in the development of complex molecules, especially in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Serves as a building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Cross-Coupling Reactions: The iodine and chlorine substituents make it an excellent substrate for sequential palladium-catalyzed cross-coupling (e.g., Suzuki, Sonogashira) to introduce diverse functional groups.
• Chemical Library Synthesis: Employed in combinatorial and parallel synthesis to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	2,3-Dichloro-5-Iodopyrazine
CAS No.	1816294-11-7
Molecular Formula	C4HCl2IN2
Molecular Weight	274.87 g/mol
Synonyms	5-Iodo-2,3-dichloropyrazine; 2,3-Dichloro-5-iodopyrazine; Pyrazine, 2,3-dichloro-5-iodo-; 1816294-11-7; 2,3-Dichloro-5-iodo-pyrazine
EINECS	Contact for details

Quality Control

Our 2,3-Dichloro-5-Iodopyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to traceability and documentation supports your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. Due to its light-sensitive nature, handling should be minimized under direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.