Description

(1(10)E,2R*,5R*)-2-Methoxy-5-Acetoxyfuranogermacr-1(10)-En-6-One is a high-purity, stereochemically defined sesquiterpene lactone derivative, valued for its role as a critical synthetic intermediate and reference standard in advanced organic chemistry. Its complex furanogermacrane skeleton makes it a compound of significant interest for research and development in pharmaceutical and fine chemical synthesis. This product is essential for R&D chemists and process development scientists working on novel bioactive molecules, natural product synthesis, and the development of new synthetic methodologies.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of novel drug candidates, particularly those with anti-inflammatory or cytotoxic activity.
• Natural Product Synthesis: Used as a sophisticated precursor in the total synthesis of complex sesquiterpenoids and related natural products.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development, quality control, and structural elucidation in research laboratories.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a defined molecular scaffold for derivatization and biological testing.
• Fine Chemical Synthesis: Acts as a specialty intermediate for creating complex, high-value fragrance or flavor molecules.
• Academic Research: Supports investigations in synthetic organic chemistry, catalysis (e.g., asymmetric synthesis), and reaction mechanism studies.

Basic Information

Product Name	(1(10)E,2R*,5R*)-2-Methoxy-5-Acetoxyfuranogermacr-1(10)-En-6-One
CAS No.	1809980-25-3
Molecular Formula	C18H24O5
Molecular Weight	320.38 g/mol
Synonyms	2-Methoxy-5-acetoxyfuranogermacr-1(10)-en-6-one; (1(10)E,2R*,5R*)-2-Methoxy-5-acetyloxyfuranogermacr-1(10)-en-6-one; Furanogermacrane-6-one, 2-methoxy-5-acetoxy-; 5-Acetoxy-2-methoxyfuranogermacr-1(10)-en-6-one; (E)-2-Methoxy-5-acetoxyfuranogermacr-1(10)-en-6-one; Germacrane sesquiterpene lactone derivative; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (1(10)E,2R*,5R*)-2-Methoxy-5-Acetoxyfuranogermacr-1(10)-En-6-One is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and MS to confirm identity, stereochemistry, and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment. We can support development projects with custom purity grades and analytical data packages upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.