Description

tert-Butyl (S)-3-Oxohexahydroimidazo[1,5-A]Pyrazine-7(1H)-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its chiral, bicyclic imidazopyrazine structure. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules, particularly in modern drug discovery pipelines. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including protease inhibitors and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of complex drug candidates, particularly those targeting enzymatic pathways.
• Protease Inhibitor Development: Serves as a core scaffold or precursor in the research and production of protease inhibitor类药物, a major class of antiviral and anticancer therapeutics.
• Peptidomimetic Chemistry: Used in constructing peptidomimetic structures designed to mimic natural peptides with enhanced metabolic stability and bioavailability.
• Asymmetric Synthesis: Leverages its defined (S)-configuration for introducing stereochemical complexity in target molecules during medicinal chemistry campaigns.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs supporting outsourced drug discovery and development programs for global clients.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and new synthetic methodologies.

Basic Information

Item	Details
Product Name	tert-Butyl (S)-3-Oxohexahydroimidazo[1,5-A]Pyrazine-7(1H)-Carboxylate
CAS No.	1808248-64-7
Molecular Formula	C11H17N3O3
Molecular Weight	239.27 g/mol
Synonyms	(S)-tert-Butyl 3-oxohexahydroimidazo[1,5-a]pyrazine-7(1H)-carboxylate; (S)-7-(tert-Butoxycarbonyl)-3-oxohexahydroimidazo[1,5-a]pyrazine; (S)-Boc-3-oxo-hexahydroimidazo[1,5-a]pyrazine; tert-Butyl (S)-3-oxo-1,2,3,5,6,7-hexahydroimidazo[1,5-a]pyrazine-7-carboxylate; (S)-3-Oxo-7-Boc-hexahydroimidazo[1,5-a]pyrazine; CAS 1808248-64-7; (S)-Boc-3-oxoimidazopyrazine
EINECS	Contact for details

Quality Control

Every batch of tert-Butyl (S)-3-Oxohexahydroimidazo[1,5-A]Pyrazine-7(1H)-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity compliance with client specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use and inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.