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1,4-Piperazinedicarboxylic Acid, 2-(Aminomethyl)-, 1,4-Bis(1,1-Dimethylethyl) Ester, (2S)- CAS NO 1808248-63-6


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CAS No.:1808248-63-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,4-Piperazinedicarboxylic Acid, 2-(Aminomethyl)-, 1,4-Bis(1,1-Dimethylethyl) Ester, (2S)- is a high-purity, chiral piperazine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its protected amine and carboxylic acid functionalities, which enable precise and efficient construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, including protease inhibitors and other small molecule therapeutics.
  • Agrochemical Synthesis: Used in the production of advanced, high-performance crop protection agents and pesticides.
  • Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal complexation.
  • Peptidomimetics Research: Integral for constructing peptide analogs and mimetics in medicinal chemistry programs.
  • Custom Chemical Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
  • Academic Research: A valuable reagent for universities and institutes studying heterocyclic chemistry and synthetic methodology.

Basic Information

Product Name 1,4-Piperazinedicarboxylic Acid, 2-(Aminomethyl)-, 1,4-Bis(1,1-Dimethylethyl) Ester, (2S)-
CAS No. 1808248-63-6
Molecular Formula C16H31N3O4
Molecular Weight 329.44 g/mol
Synonyms (2S)-2-(Aminomethyl)-1,4-bis(tert-butoxycarbonyl)piperazine; (2S)-1,4-Di-Boc-2-(aminomethyl)piperazine; 1,4-Di-Boc-2-(aminomethyl)piperazine, (S)-; tert-Butyl (2S)-2-(aminomethyl)-1,4-piperazinedicarboxylate; 1,4-Bis(tert-butoxycarbonyl)-2-(aminomethyl)piperazine, (S)-; (S)-1,4-Bis(tert-butoxycarbonyl)-2-(aminomethyl)piperazine; (S)-2-(Aminomethyl)-1,4-bis(tert-butoxycarbonyl)piperazine; 1,4-Boc-2-(Aminomethyl)piperazine (S)-enantiomer
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Quality Control

Our 1,4-Piperazinedicarboxylic Acid, 2-(Aminomethyl)-, 1,4-Bis(1,1-Dimethylethyl) Ester, (2S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 98.0%
Chiral Purity (HPLC) ≥ 99.0% ee
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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