Description

Cis,Rel-(4Ar,7As)-Octahydrocyclopenta[B]Morpholine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry, essential for the synthesis of complex active pharmaceutical ingredients (APIs). Its value lies in providing a critical, structurally rigid bicyclic scaffold that enables precise molecular construction in medicinal chemistry. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutics, particularly within the central nervous system (CNS) and antiviral drug discovery pipelines. We supply this material globally with a commitment to stringent quality control and reliable batch-to-batch consistency.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the multi-step synthesis of proprietary drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• CNS Drug Development: Employed in the research and synthesis of potential treatments for neurological disorders, leveraging its morpholine-containing structure.
• Antiviral Compound Synthesis: Acts as a precursor in the development of novel antiviral medications.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-Up: Supplied for route scouting, process development, and cGMP manufacturing of clinical trial materials.

Basic Information

Product Name	Cis,Rel-(4Ar,7As)-Octahydrocyclopenta[B]Morpholine Hydrochloride
CAS No.	1807941-05-4
Molecular Formula	C9H16ClNO
Molecular Weight	189.68 g/mol
Synonyms	(4aR,7aS)-Octahydrocyclopenta[b][1,4]oxazine hydrochloride; cis-Octahydro-2H-cyclopenta[b][1,4]oxazine hydrochloride; Rel-(4aR,7aS)-Octahydrocyclopenta[b]morpholine HCl; Bicyclo[3.3.0]octane-fused morpholine hydrochloride; 1,4-Oxazino[4,3-a]cyclopentane, octahydro-, hydrochloride, (4aR,7aS)-rel-; CPBM-HCl
EINECS	Contact for details

Quality Control

Every batch of Cis,Rel-(4Ar,7As)-Octahydrocyclopenta[B]Morpholine Hydrochloride is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards for advanced pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing purity, chiral purity, identity, and impurity profiles as confirmed by advanced analytical techniques including HPLC, GC, and NMR.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.