Description

C18-Peg4-Amine CAS NO 1807537-36-5 is a high-purity, non-ionic surfactant and linker molecule featuring a long C18 alkyl chain and a tetraethylene glycol spacer terminated with a primary amine group. This unique amphiphilic structure is critical for creating stable, functionalized surfaces and nanoparticles, enabling precise control over surface properties and bio-conjugation. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors who require reliable, high-quality functional linkers for drug delivery systems, diagnostic assays, and surface modification.

Application

• Lipid Nanoparticle (LNP) Formulation: As a PEGylated lipid component for stabilizing and targeting mRNA and siRNA delivery systems.
• Surface Functionalization: For modifying gold nanoparticles, quantum dots, and other nanomaterials to impart stealth properties and enable subsequent bioconjugation.
• Bioconjugation & Protein Modification: Acting as a heterobifunctional crosslinker to attach hydrophobic molecules or labels to proteins, antibodies, and other biomolecules via the reactive amine group.
• Liposome & Micelle Preparation: As a key excipient to enhance the stability, circulation time, and functionalization capability of lipid-based drug carriers.
• Diagnostic Assay Development: For immobilizing capture molecules on sensor surfaces or microspheres in lateral flow assays and biosensors.
• Polymer & Dendrimer Synthesis: Serving as a monomer or functionalization agent in the synthesis of amphiphilic polymers and dendrimers for biomedical applications.

Basic Information

Product Name	C18-Peg4-Amine
CAS No.	1807537-36-5
Molecular Formula	C30H63NO5
Molecular Weight	517.8 g/mol
Synonyms	18:0 PEG4 Amine; Stearyl-PEG4-Amine; Octadecyl-PEG4-Amine; C18-PEG4-NH2; 2,5,8,11-Tetraoxatetradecan-14-amine, 14-octadecyl-; N-(Octadecyl)-3,6,9,12-tetraoxapentadecan-1-amine; Poly(ethylene glycol) methyl ether stearylamine (approx. 4 EO units); DSPE-PEG(2000)-Amine analog (short chain)
EINECS	Contact for details

Quality Control

Every batch of C18-Peg4-Amine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports applications in GMP and research environments where reliable specification and traceability are paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) after opening to prevent degradation. Long-term storage at -20°C is recommended.

Specification

Item	Specification
Appearance	White to off-white waxy solid or viscous liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.