Description

tert-Butyl 4-(3-Bromo-5-Chlorophenyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with halogenated aromatic substitution. This compound is of significant value for its role as a versatile building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially those targeting neurological receptors.
• Chemical Synthesis Building Block: Used in coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the (3-bromo-5-chlorophenyl)piperazine moiety into more complex molecular architectures.
• Ligand and Probe Development: Serves as a core structure for creating chemical probes and ligands in biochemical and pharmacological research.
• Agrochemical Research: Potential application as an intermediate in the synthesis of new crop protection agents.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and structure-activity relationship (SAR) studies.

Basic Information

Product Name	tert-Butyl 4-(3-Bromo-5-Chlorophenyl)Piperazine-1-Carboxylate
CAS No.	1807447-29-5
Molecular Formula	C15H20BrClN2O2
Molecular Weight	375.69 g/mol
Synonyms	1-Boc-4-(3-Bromo-5-Chlorophenyl)Piperazine; tert-Butyl 4-(3-Bromo-5-Chlorophenyl)-1-piperazinecarboxylate; 4-(3-Bromo-5-Chlorophenyl)-N-Boc-piperazine; 1-(tert-Butoxycarbonyl)-4-(3-bromo-5-chlorophenyl)piperazine; 1807447-29-5; (3-Bromo-5-Chlorophenyl)Piperazine-1-Carboxylic Acid tert-Butyl Ester; Boc-4-(3-Bromo-5-Chlorophenyl)Piperazine
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Bromo-5-Chlorophenyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation (NMR, IR, MS), and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.