Description

2-Chloro-4-Fluoro-5-Methylbenzoyl Chloride is a high-purity, multi-functional aromatic acid chloride intermediate essential for advanced organic synthesis. This compound matters for its role as a key building block in the development of complex molecules, offering precise reactivity for introducing specific halogenated benzoyl groups. It is primarily needed by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides where the chloro-fluoro-methyl substitution pattern confers specific biological activity.
• Liquid Crystal & OLED Material Precursor: Serves as a key monomer for constructing complex aromatic cores in electronic and display materials.
• Polymer Modification Agent: Employed to introduce functional benzoyl groups into polymer chains to alter material properties.
• Organic Synthesis Reagent: A versatile reagent for Friedel-Crafts acylation and nucleophilic acyl substitution reactions in fine chemical production.
• Dyestuff & Pigment Intermediate: Used in the synthesis of specialized halogenated dyes and pigments.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Methylbenzoyl Chloride
CAS No.	1807027-18-4
Molecular Formula	C8H5Cl2FO
Molecular Weight	207.03 g/mol
Synonyms	5-Methyl-2-chloro-4-fluorobenzoyl chloride; 2-Chloro-4-fluoro-5-methylbenzoic acid chloride; 2-Chloro-4-fluoro-5-methyl-benzoyl chloride; Benzoyl chloride, 2-chloro-4-fluoro-5-methyl-; 1807027-18-4; 2-Chloro-4-fluoro-5-methylbenzenecarbonyl chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Fluoro-5-Methylbenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature and reactivity as a strong acid/organic solvent derivative, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent hydrolysis and degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.