Description

n-[4-[[4-(1-Methylethyl)-1-Piperazinyl]Sulfonyl]Phenyl]-2-Nitro-4-(Trifluoromethyl)Benzamide Hydrochloride is a high-purity, complex organic intermediate with significant potential in advanced pharmaceutical research and development. This compound is valued for its intricate molecular architecture, which incorporates key functional groups like a sulfonylpiperazine and a nitro-trifluoromethyl benzamide moiety. It is primarily targeted at research chemists and process development scientists in the pharmaceutical and agrochemical industries working on novel active ingredients. The hydrochloride salt form enhances its stability and handling properties for synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Chemical Biology Research: Used as a probe or precursor in studying enzyme inhibition and receptor-ligand interactions due to its specific structural features.
• Agrochemical Development: Acts as a key intermediate in the research and synthesis of advanced crop protection agents and pesticides.
• Material Science Research: Investigated for the development of specialty polymers or advanced organic materials with unique properties.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization studies for the commercial-scale production of complex molecules.

Basic Information

Item	Details
Product Name	n-[4-[[4-(1-Methylethyl)-1-Piperazinyl]Sulfonyl]Phenyl]-2-Nitro-4-(Trifluoromethyl)Benzamide Hydrochloride
CAS No.	1803003-68-0
Molecular Formula	C21H22F3N5O5S · HCl
Molecular Weight	558.95 g/mol (Free base: 521.49 g/mol)
Synonyms	4'-[(4-Isopropyl-1-piperazinyl)sulfonyl]-2-nitro-4-(trifluoromethyl)[1,1'-biphenyl]-3-carboxamide hydrochloride; 2-Nitro-4-(trifluoromethyl)-N-[4-[(4-propan-2-ylpiperazin-1-yl)sulfonyl]phenyl]benzamide hydrochloride; Isopropylpiperazine sulfonyl benzamide hydrochloride derivative; [4-(4-Isopropylpiperazine-1-sulfonyl)phenyl]amide of 2-nitro-4-trifluoromethylbenzoic acid hydrochloride
EINECS	Contact for details

Quality Control

Our n-[4-[[4-(1-Methylethyl)-1-Piperazinyl]Sulfonyl]Phenyl]-2-Nitro-4-(Trifluoromethyl)Benzamide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Assay (Titration)	98.0 - 102.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.