Description

(1R,4R)-4-Methoxycyclohexane-1-Carbaldehyde is a high-purity chiral aldehyde building block of significant interest in advanced organic synthesis. Its defined stereochemistry and functional group versatility make it a critical intermediate for constructing complex, optically active molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in asymmetric synthesis, medicinal chemistry, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Asymmetric Catalysis & Ligand Synthesis: Serves as a precursor for the development of chiral ligands, auxiliaries, and catalysts used in enantioselective transformations.
• Agrochemical Research: Used in the R&D of new herbicides, fungicides, and insecticides where specific stereochemistry is crucial for biological activity.
• Flavor & Fragrance Chemistry: Employed as a building block for the synthesis of stereochemically defined aroma chemicals and specialty odorants.
• Material Science: A potential monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic & Contract Research: A valuable reagent for methodological studies in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	(1R,4R)-4-Methoxycyclohexane-1-Carbaldehyde
CAS No.	1802680-45-0
Molecular Formula	C8H14O2
Molecular Weight	142.20 g/mol
Synonyms	(1R,4R)-4-Methoxycyclohexanecarboxaldehyde; (1R,4R)-4-Methoxy-1-cyclohexanecarbaldehyde; trans-4-Methoxycyclohexanecarbaldehyde; (1R,4R)-p-Methoxycyclohexanecarbaldehyde; (1R,4R)-4-Methoxy-cyclohexanecarboxaldehyde; (1R,4R)-4-Methoxycyclohexylcarboxaldehyde; (1R,4R)-4-Methoxy-1-formylcyclohexane
EINECS	Contact for details

Quality Control

Our (1R,4R)-4-Methoxycyclohexane-1-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chiral purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes data for chiral purity (enantiomeric excess), chemical purity (HPLC/GC), identity confirmation (IR, NMR), and specific tests for residual solvents and impurities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.