Description

(5-Chloropyrazin-2-Yl)Methanamine Hydrochloride is a high-purity organic salt building block of significant interest in advanced chemical synthesis. This compound matters as a key intermediate for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides where the pyrazine core offers unique biological activity.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for metal-organic catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a building block for creating molecular probes and tool compounds used in biochemical and cellular assay development.
• Material Science Research: Utilized in the synthesis of organic electronic materials and functional polymers due to the electron-deficient nature of the chloropyrazine moiety.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	(5-Chloropyrazin-2-Yl)Methanamine Hydrochloride
CAS No.	1794737-26-0
Molecular Formula	C5H7Cl2N3
Molecular Weight	180.04 g/mol
Synonyms	1-(5-Chloropyrazin-2-yl)methanamine hydrochloride; (5-Chloro-2-pyrazinyl)methanamine hydrochloride; 2-(Aminomethyl)-5-chloropyrazine hydrochloride; 5-Chloro-2-pyrazinemethanamine hydrochloride; 5-Chloropyrazine-2-methylamine hydrochloride; 2-Aminomethyl-5-chloropyrazine HCl; 5-Chloro-2-(aminomethyl)pyrazine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Chloropyrazin-2-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.