Description

Sodium 7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate is a high-purity, protected heterocyclic building block essential for advanced pharmaceutical synthesis. This compound serves as a critical intermediate in the development of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets. It is primarily utilized by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, especially those containing fused triazolopyrazine scaffolds.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a standardized starting material for scaling up synthetic routes under current Good Manufacturing Practice (cGMP) conditions.
• API Synthesis: Integral intermediate in the multi-step synthesis of final active pharmaceutical ingredients targeting neurological and psychiatric disorders.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: Foundation for the custom manufacturing of bespoke compounds for preclinical and clinical trial applications.

Basic Information

Item	Details
Product Name	Sodium 7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate
CAS No.	1788041-59-7
Molecular Formula	C11H15N4NaO4
Molecular Weight	290.26 g/mol
Synonyms	7-(Boc)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylic acid sodium salt; Sodium 7-Boc-5,6,7,8-tetrahydrotriazolopyrazine-3-carboxylate; 7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylic acid sodium salt; Boc-THPTP-COONa; 1788041-59-7; Sodium 7-(tert-butoxycarbonyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate
EINECS	Contact for details

Quality Control

Our Sodium 7-(tert-Butoxycarbonyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazine-3-carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under dry, inert conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.