Description

tert-Butyl 4-(1-Methoxycyclopropanecarbonyl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with a unique methoxycyclopropanecarbonyl substituent. This compound is critical for medicinal chemistry research and development, offering a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization to introduce specific steric and electronic properties into molecular scaffolds.
• API Development: Serves as a precursor in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs) under cGMP conditions.
• Chemical Biology Probes: Employed in the design and synthesis of chemical probes for studying biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) providing bespoke chemical synthesis services.

Basic Information

Product Name	tert-Butyl 4-(1-Methoxycyclopropanecarbonyl)Piperazine-1-Carboxylate
CAS No.	1788041-47-3
Molecular Formula	C14H24N2O4
Molecular Weight	284.35 g/mol
Synonyms	1-Boc-4-(1-Methoxycyclopropanecarbonyl)piperazine; tert-Butyl 4-(1-methoxycyclopropanecarbonyl)piperazine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(1-methoxycyclopropanecarbonyl)piperazine; 1-Methoxycyclopropanecarboxylic acid 1-Boc-piperazin-4-yl ester; 1-Boc-piperazine-4-carboxylic acid 1-methoxycyclopropyl ester; 4-(1-Methoxycyclopropanecarbonyl)piperazine-1-carboxylic acid tert-butyl ester; BOC-Piperazine-1-Methoxycyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1-Methoxycyclopropanecarbonyl)Piperazine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support development and commercial projects with material suitable for research use and can provide material manufactured under cGMP guidelines for advanced clinical stage applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.