Description

(S)-2-(Pyrrolidin-3-Yl)Isoindolin-1-One Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is of significant value for the research and development of novel therapeutic agents, particularly in the central nervous system (CNS) and oncology fields. It is primarily needed by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a component for constructing linkers or ligands in bifunctional degrader molecules.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Asymmetric Synthesis: Employed as a chiral scaffold or auxiliary in stereoselective synthetic routes.
• Reference Standard: Serves as an analytical standard for quality control and method development in API manufacturing.

Basic Information

Product Name	(S)-2-(Pyrrolidin-3-Yl)Isoindolin-1-One Hydrochloride
CAS No.	1787191-35-8
Molecular Formula	C12H15ClN2O
Molecular Weight	238.71 g/mol
Synonyms	(S)-2-(3-Pyrrolidinyl)isoindolin-1-one hydrochloride; (S)-1-Oxo-2-(pyrrolidin-3-yl)isoindoline hydrochloride; (3S)-2-(3-Pyrrolidinyl)-1H-isoindol-1-one hydrochloride; (S)-2-(Pyrrolidin-3-yl)isoindolin-1-one HCl; 1H-Isoindol-1-one, 2-(3-pyrrolidinyl)-, hydrochloride, (3S)-; 1787191-35-8
EINECS	Contact for details

Quality Control

Our (S)-2-(Pyrrolidin-3-Yl)Isoindolin-1-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee reliable and reproducible performance in your critical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.