Description

6-Phenyl-Piperidine-3-Carboxylic Acid Methyl Ester is a high-purity, synthetically versatile piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized chiral scaffold essential for constructing complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides requiring specific stereochemistry.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new reaction pathways.
• Fine Chemical Production: Integral to the multi-step synthesis of complex, high-value specialty chemicals and flavors/fragrances.

Basic Information

Product Name	6-Phenyl-Piperidine-3-Carboxylic Acid Methyl Ester
CAS No.	1784107-97-6
Molecular Formula	C14H19NO2
Molecular Weight	233.31 g/mol
Synonyms	Methyl 6-phenylpiperidine-3-carboxylate; 3-Carbomethoxy-6-phenylpiperidine; 6-Phenyl-3-piperidinecarboxylic acid methyl ester; Methyl 6-phenyl-3-piperidinecarboxylate; 6-Phenylnipecotic acid methyl ester; 1,2,3,6-Tetrahydropyridine-3-carboxylic acid, 6-phenyl-, methyl ester (related); Piperidine-3-carboxylic acid, 6-phenyl-, methyl ester
EINECS	Contact for details

Quality Control

Our 6-Phenyl-Piperidine-3-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee (by Chiral HPLC)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.