Description

2-[(tert-Butoxy)Carbonyl]-1H,2H,3H,4H-Pyrrolo[1,2-A]Pyrazine-7-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex molecules, enabling the creation of novel therapeutic agents with enhanced efficacy. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of innovative small-molecule drugs, particularly within oncology and central nervous system (CNS) research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel active pharmaceutical ingredients (APIs) for clinical research.
• Drug Discovery & Development: Used in medicinal chemistry for lead optimization and the construction of complex heterocyclic scaffolds.
• Proteolysis Targeting Chimera (PROTAC) Synthesis: Serves as a component in the linker or warhead design for targeted protein degradation therapeutics.
• Chemical Biology Research: Employed as a tool compound for studying biological pathways and protein-ligand interactions.
• Process Chemistry & Scale-Up: Supports route scouting and optimization for the commercial-scale manufacturing of candidate drugs.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global pharmaceutical pipelines.

Basic Information

Item	Detail
Product Name	2-[(tert-Butoxy)Carbonyl]-1H,2H,3H,4H-Pyrrolo[1,2-A]Pyrazine-7-Carboxylic Acid
CAS No.	1782248-68-3
Molecular Formula	C14H20N2O4
Molecular Weight	280.32 g/mol
Synonyms	1,2,3,4-Tetrahydro-7-pyrrolo[1,2-a]pyrazinecarboxylic acid, 2-[(1,1-dimethylethoxy)carbonyl]-; 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid; Boc-Pyrrolo[1,2-a]pyrazine-7-carboxylic acid; 2-Boc-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-7-carboxylic acid; 7-Carboxy-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine; 2-(tert-Butoxycarbonyl)-1,2,3,4-tetrahydro-7H-pyrrolo[1,2-a]pyrazine-7-carboxylic acid
EINECS	Contact for details

Quality Control

Our 2-[(tert-Butoxy)Carbonyl]-1H,2H,3H,4H-Pyrrolo[1,2-A]Pyrazine-7-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.