Description

3-Chloro-8-Methoxy-Imidazo[1,2-A]Pyrazine is a high-purity, heterocyclic organic compound with the CAS number 1780010-11-8, serving as a critical advanced intermediate in modern pharmaceutical and agrochemical research. Its unique fused-ring structure makes it a valuable scaffold for synthesizing novel active ingredients, particularly in the development of targeted small-molecule therapeutics. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, aiming to create new drug candidates with specific biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for oncology, antiviral, and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis to explore new chemical entities.
• Agrochemical Development: Serves as an intermediate in the research and production of new-generation pesticides and herbicides.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying biological pathways and target validation.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting the pharmaceutical and agrochemical industries with custom synthesis.

Basic Information

Product Name	3-Chloro-8-Methoxy-Imidazo[1,2-A]Pyrazine
CAS No.	1780010-11-8
Molecular Formula	C7H6ClN3O
Molecular Weight	183.59 g/mol
Synonyms	3-Chloro-8-methoxyimidazo[1,2-a]pyrazine; Imidazo[1,2-a]pyrazine, 3-chloro-8-methoxy-; 8-Methoxy-3-chloroimidazo[1,2-a]pyrazine; 3-Chloro-8-methoxy-imidazo[1,2-a]pyrazine; 1780010-11-8; SCHEMBL23883027; ZINC000000000000; AKOS040759232; FT-0775787
EINECS	Contact for details

Quality Control

Our 3-Chloro-8-Methoxy-Imidazo[1,2-A]Pyrazine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for demanding research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every batch upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.