Description

4-(2-Amino-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a key Boc-protected piperazine derivative, serving as a versatile and critical building block in advanced organic synthesis. Its primary value lies in providing a protected amine functionality, enabling precise and efficient multi-step synthesis of complex molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and plant growth regulators that require complex amine scaffolds.
• Peptidomimetics & Bioconjugation: Serves as a spacer or linker unit in the design of peptide mimics and for the conjugation of bioactive molecules.
• Chemical Biology Probes: Employed in the creation of specialized probes and tool compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing high-value specialty chemicals.
• Academic & Industrial R&D: Supports fundamental research in organic chemistry and process development for scaling novel synthetic routes.

Basic Information

Product Name	4-(2-Amino-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1779927-90-0
Molecular Formula	C13H27N3O2
Molecular Weight	257.38 g/mol
Synonyms	1-Boc-4-(2-aminopropyl)piperazine; tert-Butyl 4-(2-aminopropyl)piperazine-1-carboxylate; 4-(2-Aminopropyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(2-aminopropyl)piperazine; N-Boc-4-(2-aminopropyl)piperazine; Piperazine-1-carboxylic acid, 4-(2-aminopropyl)-, 1,1-dimethylethyl ester; Boc-4-(2-aminopropyl)piperazine
EINECS	Contact for details

Quality Control

Our 4-(2-Amino-Propyl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for sensitive synthetic applications. Certificates of Analysis (COA) with full traceability are provided to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.