Description

tert-Butyl 4-(2-Nitropyridin-3-yl)piperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperazine core with a nitropyridine substituent. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop new molecular entities.
• API Synthesis: Serves as a crucial building block in multi-step synthetic routes for the production of potential active pharmaceutical ingredients.
• Chemical Library Development: Employed in the construction of diverse compound libraries for high-throughput screening (HTS) in drug discovery.
• Process Chemistry: Used in the development and scale-up of efficient, robust synthetic processes for pharmaceutical manufacturing.
• Academic Research: Utilized in university and institutional labs for studies in organic synthesis, heterocyclic chemistry, and pharmacology.

Basic Information

Product Name	tert-Butyl 4-(2-Nitropyridin-3-yl)piperazine-1-carboxylate
CAS No.	1779124-68-3
Molecular Formula	C14H20N4O4
Molecular Weight	308.33 g/mol
Synonyms	1-Boc-4-(2-nitro-3-pyridyl)piperazine; tert-Butyl 4-(2-nitro-3-pyridinyl)-1-piperazinecarboxylate; 3-(4-Boc-piperazin-1-yl)-2-nitropyridine; 2-Nitro-3-(4-(tert-butoxycarbonyl)piperazin-1-yl)pyridine; 1-(tert-Butoxycarbonyl)-4-(2-nitro-3-pyridyl)piperazine; Boc-4-(2-nitro-3-pyridyl)piperazine; 1779124-68-3
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(2-Nitropyridin-3-yl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.