Description

Ketoprofen Tromethamine Amide is a key pharmaceutical intermediate and derivative of the non-steroidal anti-inflammatory drug (NSAID) ketoprofen. This compound is of significant commercial interest for the development of novel drug formulations and prodrugs aimed at enhancing bioavailability and reducing gastrointestinal side effects. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in advanced analgesic and anti-inflammatory therapeutic development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of new ketoprofen derivatives and prodrug candidates.
• Analgesic & Anti-inflammatory Research: Used in preclinical and clinical research for developing next-generation NSAID formulations with improved safety profiles.
• Prodrug Synthesis: The amide functional group makes it a versatile precursor for creating prodrugs designed for targeted release and enhanced patient compliance.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Chemical Synthesis: Utilized in organic synthesis for introducing the ketoprofen pharmacophore into more complex molecular architectures.
• Academic & Industrial R&D: Fundamental research in medicinal chemistry and pharmacology to explore new mechanisms of action and therapeutic applications.

Basic Information

Product Name	Ketoprofen Tromethamine Amide
CAS No.	1777830-05-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ketoprofen Tromethamine Amide; Tromethamine salt of Ketoprofen amide; Ketoprofen Trometamol Amide; 2-(3-Benzoylphenyl)propanoic acid tromethamine amide; Ketoprofen TRIS Amide; (RS)-2-(3-Benzoylphenyl)propionic acid tromethamine amide; Ketoprofen Tromethamine derivative
EINECS	Contact for details

Quality Control

Our Ketoprofen Tromethamine Amide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm
Assay	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.